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KMID : 0829320070100010054
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Korean Journal of Clinical Microbiology
2007 Volume.10 No. 1 p.54 ~ p.58
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Evaluation of SD Bioline Strep A for Rapid Antigen Testing in Elementary Schoolchildren
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Koh Eun-Ha
Kim Sun-Joo
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Abstract
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Background: Rapid antigen tests (RAT) of group A streptococci (GAS) are easy to perform and can save two days of bacterial culture time. Performance of SD Bioline Strep A was analyzed in comparison with throat culture.
Methods: Three consecutive throat swabs were taken from 308 healthy elementary schoolchildren. The first two swabs were tested for SD Bioline Strep A and Quidel Quick Vue Dipstick Strep A rapid antigen tests, and the third one was inoculated onto blood agar plate to grow GAS.
Results: Sensitivity, specificity, positive predictive value and negative predictive value of SD Bioline Strep A were 79.3%, 88.9%, 72.2%, and 92.2% respectively. Those of Quidel Quick Vue Strep A were 58.5%, 93.8%, 77.4%, and 86.2% respectively.
Conclusion: SD Bioline Strep A showed a significantly higher sensitivity and a slightly lower specificity compared to Quidel Quick Vue Strep A. SD Bioline Strep A RAT should be useful for the rapid diagnosis of bacterial pharyngitis and the optimum use of antibiotics. (Korean J Clin Microbiol 2007;10:54-58)
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KEYWORD
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Streptococcus pyogenes, Group A streptococcus, Rapid antigen test, Throat culture, Pharyngitis
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